By Henry H Q Heng
Cancer study is at a crossroads. typically, melanoma has been regarded as a affliction of gene mutation, the place the stepwise accumulation of melanoma gene mutations is the foremost, and the id of universal gene mutations has been thought of to be crucial for prognosis and remedy. regardless of large examine efforts and amassed wisdom on melanoma genes and pathways, the scientific advantages of this conventional method were restricted. lately, melanoma genome sequencing has published an in depth volume of genetic heterogeneity the place the long-expected universal mutation drivers were tricky, if now not very unlikely, to spot. those realities finally problem the conceptual framework of present melanoma biology.
This publication introduces a brand new suggestion of genome idea of melanoma evolution, in an try and unify the sphere. Many vital and consultant, yet frequently complicated, questions and paradoxes are significantly analyzed. by means of evaluating gene- and genome-based theories, the hidden flaws of many renowned viewpoints are addressed. This dialogue is meant to start up a much-needed severe second look of present melanoma research.
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Extra resources for Debating Cancer:The Paradox in Cancer Research
Debating Cancer:The Paradox in Cancer Research by Henry H Q Heng